HCR hairpin
Multiplexed In Situ HCR

Next-generation DNA HCR kits provide researchers with:

  • amplification for up to five target mRNAs at a time
  • deep sample penetration
  • high signal-to-background
  • subcellular or single-molecule resolution as desired
  • compatibility with tissue clearing in diverse model and non-model organisms

Simultaneous mapping of four target mRNAs within a fixed whole-mount zebrafish embryo. (pdf, movie)
Multiplexed mRNA expression maps using in situ HCR.
(pdf, movies: fruit fly, sea urchin, zebrafish, chicken, mouse)